FANCD2 Confers a Malignant Phenotype in Esophageal Squamous Cell Carcinoma by Regulating Cell Cycle Progression

SIMPLE SUMMARY: Fanconi anemia patients with germline FANCD2 defects are susceptible to cancers. In order to understand FANCD2 function in esophageal cancers, we used cell line, animal model, and sequencing approaches. We knocked out the FANCD2 gene and examined the functional impact of its loss on...

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Detalles Bibliográficos
Autores principales: Lei, Lisa Chan, Yu, Valen Zhuoyou, Ko, Josephine Mun Yee, Ning, Lvwen, Lung, Maria Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565464/
https://www.ncbi.nlm.nih.gov/pubmed/32906798
http://dx.doi.org/10.3390/cancers12092545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565464/
https://www.ncbi.nlm.nih.gov/pubmed/32906798
http://dx.doi.org/10.3390/cancers12092545

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