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pH-Channeling in Cancer: How pH-Dependence of Cation Channels Shapes Cancer Pathophysiology
Tissue acidosis plays a pivotal role in tumor progression: in particular, interstitial acidosis promotes tumor cell invasion, and is a major contributor to the dysregulation of tumor immunity and tumor stromal cells. The cell membrane and integral membrane proteins commonly act as important sensors...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565548/ https://www.ncbi.nlm.nih.gov/pubmed/32887220 http://dx.doi.org/10.3390/cancers12092484 |