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Truncated PPM1D Prevents Apoptosis in the Murine Thymus and Promotes Ionizing Radiation-Induced Lymphoma

Genome integrity is protected by the cell-cycle checkpoints that prevent cell proliferation in the presence of DNA damage and allow time for DNA repair. The transient checkpoint arrest together with cellular senescence represent an intrinsic barrier to tumorigenesis. Tumor suppressor p53 is an integ...

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Detalles Bibliográficos
Autores principales: Martinikova, Andra S., Burocziova, Monika, Stoyanov, Miroslav, Macurek, Libor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565556/
https://www.ncbi.nlm.nih.gov/pubmed/32927737
http://dx.doi.org/10.3390/cells9092068