Cargando…
Unexpectedly High Levels of Inverted Re-Insertions Using Paired sgRNAs for Genomic Deletions
Use of dual sgRNAs is a common CRISPR/Cas9-based strategy for the creation of genetic deletions. The ease of screening combined with a rather high rate of success makes this approach a reliable genome engineering procedure. Recently, a number of studies using CRISPR/Cas9 have revealed unwanted large...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565582/ https://www.ncbi.nlm.nih.gov/pubmed/32751356 http://dx.doi.org/10.3390/mps3030053 |