Severe Human Lassa Fever Is Characterized by Nonspecific T-Cell Activation and Lymphocyte Homing to Inflamed Tissues

Lassa fever (LF) is a zoonotic viral hemorrhagic fever caused by Lassa virus (LASV), which is endemic to West African countries. Previous studies have suggested an important role for T-cell-mediated immunopathology in LF pathogenesis, but the mechanisms by which T cells influence disease severity an...

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Detalles Bibliográficos
Autores principales: Port, Julia R., Wozniak, David M., Oestereich, Lisa, Pallasch, Elisa, Becker-Ziaja, Beate, Müller, Jonas, Rottstegge, Monika, Olal, Catherine, Gómez-Medina, Sergio, Oyakhliome, Jennifer, Ighodalo, Yemisi, Omomoh, Emmanuel, Olokor, Thomas, Adomeh, Donatus I., Asogun, Danny, Ogbani-Emovon, Ephraim, Hartmann, Kristin, Krasemann, Susanne, Nelson, Emily V., Escudero-Pérez, Beatriz, McElroy, Anita K., Günther, Stephan, Muñoz-Fontela, César
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565638/
https://www.ncbi.nlm.nih.gov/pubmed/32817220
http://dx.doi.org/10.1128/JVI.01367-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565638/
https://www.ncbi.nlm.nih.gov/pubmed/32817220
http://dx.doi.org/10.1128/JVI.01367-20

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