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Catabolic Reductive Dehalogenase Substrate Complex Structures Underpin Rational Repurposing of Substrate Scope

Reductive dehalogenases are responsible for the reductive cleavage of carbon-halogen bonds during organohalide respiration. A variety of mechanisms have been proposed for these cobalamin and [4Fe-4S] containing enzymes, including organocobalt, radical, or cobalt-halide adduct based catalysis. The la...

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Detalles Bibliográficos
Autores principales: Halliwell, Tom, Fisher, Karl, Payne, Karl A. P., Rigby, Stephen E. J., Leys, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565698/
https://www.ncbi.nlm.nih.gov/pubmed/32887524
http://dx.doi.org/10.3390/microorganisms8091344