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Phosphorylation of OCT4 Serine 236 Inhibits Germ Cell Tumor Growth by Inducing Differentiation

SIMPLE SUMMARY: Octamer-binding transcription factor 4 (OCT4) plays an important role in early embryonic development, but is rarely expressed in adults. However, in many cancer cells, this gene is re-expressed, making the cancer malignant. This present study revealed that inhibiting OCT4 transcripti...

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Detalles Bibliográficos
Autores principales: Kim, Dong Keon, Song, Bomin, Han, Suji, Jang, Hansol, Bae, Seung-Hyun, Kim, Hee Yeon, Lee, Seon-Hyeong, Lee, Seungjin, Kim, Jong Kwang, Kim, Han-Seong, Hong, Kyeong-Man, Lee, Byung Il, Youn, Hong-Duk, Kim, Soo-Youl, Kang, Sang Won, Jang, Hyonchol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565739/
https://www.ncbi.nlm.nih.gov/pubmed/32932964
http://dx.doi.org/10.3390/cancers12092601