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Phosphorylation of OCT4 Serine 236 Inhibits Germ Cell Tumor Growth by Inducing Differentiation
SIMPLE SUMMARY: Octamer-binding transcription factor 4 (OCT4) plays an important role in early embryonic development, but is rarely expressed in adults. However, in many cancer cells, this gene is re-expressed, making the cancer malignant. This present study revealed that inhibiting OCT4 transcripti...
Autores principales: | Kim, Dong Keon, Song, Bomin, Han, Suji, Jang, Hansol, Bae, Seung-Hyun, Kim, Hee Yeon, Lee, Seon-Hyeong, Lee, Seungjin, Kim, Jong Kwang, Kim, Han-Seong, Hong, Kyeong-Man, Lee, Byung Il, Youn, Hong-Duk, Kim, Soo-Youl, Kang, Sang Won, Jang, Hyonchol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565739/ https://www.ncbi.nlm.nih.gov/pubmed/32932964 http://dx.doi.org/10.3390/cancers12092601 |
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