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Cellular Uptake of siRNA-Loaded Nanocarriers to Knockdown PD-L1: Strategies to Improve T-cell Functions

T-cells are a type of lymphocyte (a subtype of white blood cells) that play a central role in cell-mediated immunity. Currently, adoptive T-cell immunotherapy is being developed to destroy cancer cells. In this therapy, T-cells are harvested from a patient’s blood. After several weeks of growth in c...

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Detalles Bibliográficos
Autores principales: Thiramanas, Raweewan, Li, Mengyi, Jiang, Shuai, Landfester, Katharina, Mailänder, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565787/
https://www.ncbi.nlm.nih.gov/pubmed/32906726
http://dx.doi.org/10.3390/cells9092043