Adjuvant Activity of Synthetic Lipid A of Alcaligenes, a Gut-Associated Lymphoid Tissue-Resident Commensal Bacterium, to Augment Antigen-Specific IgG and Th17 Responses in Systemic Vaccine

Alcaligenes spp. are identified as commensal bacteria and have been found to inhabit Peyer’s patches in the gut. We previously reported that Alcaligenes-derived lipopolysaccharides (LPS) exerted adjuvant activity in systemic vaccination, without excessive inflammation. Lipid A is one of the componen...

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Detalles Bibliográficos
Autores principales: Wang, Yunru, Hosomi, Koji, Shimoyama, Atsushi, Yoshii, Ken, Yamaura, Haruki, Nagatake, Takahiro, Nishino, Tomomi, Kiyono, Hiroshi, Fukase, Koichi, Kunisawa, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565795/
https://www.ncbi.nlm.nih.gov/pubmed/32698404
http://dx.doi.org/10.3390/vaccines8030395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565795/
https://www.ncbi.nlm.nih.gov/pubmed/32698404
http://dx.doi.org/10.3390/vaccines8030395

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