TIM-3 Expression Is Downregulated on Human NK Cells in Response to Cancer Targets in Synergy with Activation

Among natural killer (NK) cell receptors, the T-cell immunoglobulin and mucin-containing domain (TIM-3) has been associated with both inhibitory and activating functions, depending on context and activation pathway. Ex vivo and in vitro, expression of TIM-3 is inducible and depends on activation sti...

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Detalles Bibliográficos
Autores principales: Dao, Tram N., Utturkar, Sagar, Atallah Lanman, Nadia, Matosevic, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565804/
https://www.ncbi.nlm.nih.gov/pubmed/32858904
http://dx.doi.org/10.3390/cancers12092417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565804/
https://www.ncbi.nlm.nih.gov/pubmed/32858904
http://dx.doi.org/10.3390/cancers12092417

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