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TIM-3 Expression Is Downregulated on Human NK Cells in Response to Cancer Targets in Synergy with Activation
Among natural killer (NK) cell receptors, the T-cell immunoglobulin and mucin-containing domain (TIM-3) has been associated with both inhibitory and activating functions, depending on context and activation pathway. Ex vivo and in vitro, expression of TIM-3 is inducible and depends on activation sti...
Autores principales: | Dao, Tram N., Utturkar, Sagar, Atallah Lanman, Nadia, Matosevic, Sandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565804/ https://www.ncbi.nlm.nih.gov/pubmed/32858904 http://dx.doi.org/10.3390/cancers12092417 |
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