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Cell-Based Influenza A/H1N1pdm09 Vaccine Viruses Containing Chimeric Hemagglutinin with Improved Membrane Fusion Ability

The H1N1 influenza pandemic vaccine has been developed from the A/California/07/09 (Cal) virus and the well-known high-yield A/Puerto Rico/8/34 (PR8) virus by classical reassortment and reverse genetics (RG) in eggs. Previous studies have suggested that Cal-derived chimeric hemagglutinin (HA) and ne...

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Detalles Bibliográficos
Autores principales: Kawahara, Madoka, Wada, Toshiya, Momose, Fumitaka, Nobusawa, Eri, Morikawa, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565828/
https://www.ncbi.nlm.nih.gov/pubmed/32825107
http://dx.doi.org/10.3390/vaccines8030458