Cargando…

Identification of MicroRNA-Related Tumorigenesis Variants and Genes in the Cancer Genome Atlas (TCGA) Data

MicroRNAs (miRNAs) are a class of small non-coding RNA that can down-regulate their targets by selectively binding to the 3′ untranslated region (3′UTR) of most messenger RNAs (mRNAs) in the human genome. Single nucleotide variants (SNVs) located in miRNA target sites (MTS) can disrupt the binding o...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Chang, Wu, Brian, Han, Han, Zhao, Jeff, Bai, Yongsheng, Liu, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565843/
https://www.ncbi.nlm.nih.gov/pubmed/32824926
http://dx.doi.org/10.3390/genes11090953