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Nucleotide Loading Modes of Human RNA Polymerase II as Deciphered by Molecular Simulations
Mapping the route of nucleoside triphosphate (NTP) entry into the sequestered active site of RNA polymerase (RNAP) has major implications for elucidating the complete nucleotide addition cycle. Constituting a dichotomy that remains to be resolved, two alternatives, direct NTP delivery via the second...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565877/ https://www.ncbi.nlm.nih.gov/pubmed/32906795 http://dx.doi.org/10.3390/biom10091289 |