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Proteomic Profiling of Extracellular Vesicles Derived from Cerebrospinal Fluid of Alzheimer’s Disease Patients: A Pilot Study

Pathological hallmarks of Alzheimer’s disease (AD) are deposits of amyloid beta (Aβ) and hyper-phosphorylated tau aggregates in brain plaques. Recent studies have highlighted the importance of Aβ and tau-containing extracellular vesicles (EVs) in AD. We therefore examined EVs separated from cerebros...

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Detalles Bibliográficos
Autores principales: Muraoka, Satoshi, Jedrychowski, Mark P., Yanamandra, Kiran, Ikezu, Seiko, Gygi, Steven P., Ikezu, Tsuneya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565882/
https://www.ncbi.nlm.nih.gov/pubmed/32854315
http://dx.doi.org/10.3390/cells9091959