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Mouse WIF1 Is Only Modified with O-Fucose in Its EGF-like Domain III Despite Two Evolutionarily Conserved Consensus Sites

The Wnt Inhibitory Factor 1 (Wif1), known to inhibit Wnt signaling pathways, is composed of a WIF domain and five EGF-like domains (EGF-LDs) involved in protein interactions. Despite the presence of a potential O-fucosylation site in its EGF-LDs III and V, the O-fucose sites occupancy has never been...

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Detalles Bibliográficos
Autores principales: Pennarubia, Florian, Pinault, Emilie, Al Jaam, Bilal, Brun, Caroline E., Maftah, Abderrahman, Germot, Agnès, Legardinier, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565927/
https://www.ncbi.nlm.nih.gov/pubmed/32872229
http://dx.doi.org/10.3390/biom10091250