The Role of PARP1 in Monocyte and Macrophage Commitment and Specification: Future Perspectives and Limitations for the Treatment of Monocyte and Macrophage Relevant Diseases with PARP Inhibitors

Modulation of PARP1 expression, changes in its enzymatic activity, post-translational modifications, and inflammasome-dependent cleavage play an important role in the development of monocytes and numerous subtypes of highly specialized macrophages. Transcription of PARP1 is governed by the prolifera...

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Detalles Bibliográficos
Autores principales: Sobczak, Maciej, Zyma, Marharyta, Robaszkiewicz, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565932/
https://www.ncbi.nlm.nih.gov/pubmed/32900001
http://dx.doi.org/10.3390/cells9092040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565932/
https://www.ncbi.nlm.nih.gov/pubmed/32900001
http://dx.doi.org/10.3390/cells9092040

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