A Phase 2a Randomized, Double-Blind, Dose-Optimizing Study to Evaluate the Immunogenicity and Safety of a Bivalent DNA Vaccine for Hemorrhagic Fever with Renal Syndrome Delivered by Intramuscular Electroporation

Hantaan virus (HTNV) and Puumala virus (PUUV) are pathogenic hantaviruses found in Asia and Europe, respectively. DNA vaccines targeting the envelope glycoproteins of these viruses have been constructed and found to elicit neutralizing antibodies when delivered to humans by various technologies incl...

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Detalles Bibliográficos
Autores principales: Hooper, Jay, Paolino, K. M., Mills, K., Kwilas, S., Josleyn, M., Cohen, M., Somerville, B., Wisniewski, M., Norris, S., Hill, B., Sanchez-Lockhart, M., Hannaman, D., Schmaljohn, C. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565952/
https://www.ncbi.nlm.nih.gov/pubmed/32664486
http://dx.doi.org/10.3390/vaccines8030377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565952/
https://www.ncbi.nlm.nih.gov/pubmed/32664486
http://dx.doi.org/10.3390/vaccines8030377

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