A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology

Non-alcoholic steatohepatitis (NASH) is a fast-growing liver disorder that is associated with an increased incidence of cardiovascular disease and type 2 diabetes. Animal models adequately mimicking this condition are scarce. We herein investigate whether Ldlr−/−. Leiden mice on different high-fat d...

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Detalles Bibliográficos
Autores principales: van den Hoek, Anita M., Verschuren, Lars, Worms, Nicole, van Nieuwkoop, Anita, de Ruiter, Christa, Attema, Joline, Menke, Aswin L., Caspers, Martien P. M., Radhakrishnan, Sridhar, Salic, Kanita, Kleemann, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565967/
https://www.ncbi.nlm.nih.gov/pubmed/32883049
http://dx.doi.org/10.3390/cells9092014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565967/
https://www.ncbi.nlm.nih.gov/pubmed/32883049
http://dx.doi.org/10.3390/cells9092014

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