Rescue of Hepatic Phospholipid Remodeling Defect in iPLA(2)β-Null Mice Attenuates Obese but Not Non-Obese Fatty Liver

Polymorphisms of group VIA calcium-independent phospholipase A2 (iPLA(2)β or PLA2G6) are positively associated with adiposity, blood lipids, and Type-2 diabetes. The ubiquitously expressed iPLA(2)β catalyzes the hydrolysis of phospholipids (PLs) to generate a fatty acid and a lysoPL. We studied the...

Descripción completa

Detalles Bibliográficos
Autores principales: Chamulitrat, Walee, Jansakun, Chutima, Li, Huili, Liebisch, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565968/
https://www.ncbi.nlm.nih.gov/pubmed/32957701
http://dx.doi.org/10.3390/biom10091332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565968/
https://www.ncbi.nlm.nih.gov/pubmed/32957701
http://dx.doi.org/10.3390/biom10091332

Ejemplares similares