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Rescue of Hepatic Phospholipid Remodeling Defect in iPLA(2)β-Null Mice Attenuates Obese but Not Non-Obese Fatty Liver

Polymorphisms of group VIA calcium-independent phospholipase A2 (iPLA(2)β or PLA2G6) are positively associated with adiposity, blood lipids, and Type-2 diabetes. The ubiquitously expressed iPLA(2)β catalyzes the hydrolysis of phospholipids (PLs) to generate a fatty acid and a lysoPL. We studied the...

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Detalles Bibliográficos
Autores principales:	Chamulitrat, Walee, Jansakun, Chutima, Li, Huili, Liebisch, Gerhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565968/ https://www.ncbi.nlm.nih.gov/pubmed/32957701 http://dx.doi.org/10.3390/biom10091332

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