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Importance of Endocytosis for the Biological Activity of Cedar Virus Fusion Protein

Endocytosis plays a particular role in the proteolytic activation of highly pathogenic henipaviruses Hendra (HeV) and Nipah virus (NiV) fusion (F) protein precursors. These proteins require endocytic uptake from the cell surface to be cleaved by cellular proteases within the endosomal compartment, f...

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Detalles Bibliográficos
Autores principales: Fischer, Kerstin, Groschup, Martin H., Diederich, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565975/
https://www.ncbi.nlm.nih.gov/pubmed/32911832
http://dx.doi.org/10.3390/cells9092054