Insight into the Anticancer Activity of Copper(II) 5-Methylenetrimethylammonium-Thiosemicarbazonates and Their Interaction with Organic Cation Transporters

A series of four water-soluble salicylaldehyde thiosemicarbazones with a positively charged trimethylammonium moiety ([H(2)L(R)]Cl, R = H, Me, Et, Ph) and four copper(II) complexes [Cu(HL(R))Cl]Cl (1–4) were synthesised with the aim to study (i) their antiproliferative activity in cancer cells and,...

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Detalles Bibliográficos
Autores principales: Milunović, Miljan N. M., Palamarciuc, Oleg, Sirbu, Angela, Shova, Sergiu, Dumitrescu, Dan, Dvoranová, Dana, Rapta, Peter, Petrasheuskaya, Tatsiana V., Enyedy, Eva A., Spengler, Gabriella, Ilic, Marija, Sitte, Harald H., Lubec, Gert, Arion, Vladimir B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565988/
https://www.ncbi.nlm.nih.gov/pubmed/32825480
http://dx.doi.org/10.3390/biom10091213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565988/
https://www.ncbi.nlm.nih.gov/pubmed/32825480
http://dx.doi.org/10.3390/biom10091213

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