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High Sensitivity of Circulating Tumor Cells Derived from a Colorectal Cancer Patient for Dual Inhibition with AKT and mTOR Inhibitors

Circulating tumor cells (CTCs) are cells shed from the primary tumor into the bloodstream. While many studies on solid tumor cells exist, data on CTCs are scarce. The mortality of cancer is mostly associated with metastasis and recent research identified CTCs as initiators of metastasis. The PI3K/AK...

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Detalles Bibliográficos
Autores principales: Smit, Daniel J., Cayrefourcq, Laure, Haider, Marie-Therese, Hinz, Nico, Pantel, Klaus, Alix-Panabières, Catherine, Jücker, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566012/
https://www.ncbi.nlm.nih.gov/pubmed/32962206
http://dx.doi.org/10.3390/cells9092129