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Mild dyserythropoiesis and β-like globin gene expression imbalance due to the loss of histone chaperone ASF1B
The expression of the human β-like globin genes follows a well-orchestrated developmental pattern, undergoing two essential switches, the first one during the first weeks of gestation (ε to γ), and the second one during the perinatal period (γ to β). The γ- to β-globin gene switching mechanism inclu...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566067/ https://www.ncbi.nlm.nih.gov/pubmed/33066815 http://dx.doi.org/10.1186/s40246-020-00283-3 |