Mild dyserythropoiesis and β-like globin gene expression imbalance due to the loss of histone chaperone ASF1B

The expression of the human β-like globin genes follows a well-orchestrated developmental pattern, undergoing two essential switches, the first one during the first weeks of gestation (ε to γ), and the second one during the perinatal period (γ to β). The γ- to β-globin gene switching mechanism inclu...

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Detalles Bibliográficos
Autores principales: Papadopoulos, Petros, Kafasi, Athanassia, De Cuyper, Iris M., Barroca, Vilma, Lewandowski, Daniel, Kadri, Zahra, Veldthuis, Martijn, Berghuis, Jeffrey, Gillemans, Nynke, Cuesta, Celina María Benavente, Grosveld, Frank G., van Zwieten, Rob, Philipsen, Sjaak, Vernet, Muriel, Gutiérrez, Laura, Patrinos, George P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566067/
https://www.ncbi.nlm.nih.gov/pubmed/33066815
http://dx.doi.org/10.1186/s40246-020-00283-3

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