Human germinal centres engage memory and naïve B cells after influenza vaccination

Influenza viruses remain a major public health threat. Seasonal influenza vaccination in humans primarily stimulates pre-existing memory B cells, leading to a transient wave of circulating antibody-secreting plasmablasts(1–3). This recall response contributes to “original antigenic sin,” the selecti...

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Detalles Bibliográficos
Autores principales: Turner, Jackson S., Zhou, Julian Q., Han, Julianna, Schmitz, Aaron J., Rizk, Amena A., Alsoussi, Wafaa B., Lei, Tingting, Amor, Mostafa, McIntire, Katherine M., Meade, Philip, Strohmeier, Shirin, Brent, Rafael I., Richey, Sara T., Haile, Alem, Yang, Yuhe R., Klebert, Michael K., Suessen, Teresa, Teefey, Sharlene, Presti, Rachel M., Krammer, Florian, Kleinstein, Steven H., Ward, Andrew B., Ellebedy, Ali H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566073/
https://www.ncbi.nlm.nih.gov/pubmed/32866963
http://dx.doi.org/10.1038/s41586-020-2711-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566073/
https://www.ncbi.nlm.nih.gov/pubmed/32866963
http://dx.doi.org/10.1038/s41586-020-2711-0

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