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A foundation for reference models for drug combinations with an application to Loewe’s reference model
BACKGROUND: Treating patients with combinations of drugs that have synergistic effects has become widespread practice in the clinic. Drugs work synergistically when the observed effect of a drug combination is larger than the effect predicted by the reference model. The reference model is a theoreti...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566125/ https://www.ncbi.nlm.nih.gov/pubmed/33059599 http://dx.doi.org/10.1186/s12859-020-03771-4 |