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WTAP Function in Sertoli Cells Is Essential for Sustaining the Spermatogonial Stem Cell Niche

Sertoli cells are the major component of the spermatogonial stem cell (SSC) niche; however, regulatory mechanisms in Sertoli cells that dictate SSC fate decisions remain largely unknown. Here we revealed features of the N(6)-methyladenosine (m(6)A) mRNA modification in Sertoli cells and demonstrated...

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Detalles Bibliográficos
Autores principales: Jia, Gong-Xue, Lin, Zhen, Yan, Rong-Ge, Wang, Guo-Wen, Zhang, Xiao-Na, Li, Cen, Tong, Ming-Han, Yang, Qi-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566211/
https://www.ncbi.nlm.nih.gov/pubmed/33053361
http://dx.doi.org/10.1016/j.stemcr.2020.09.001