Association Between DNA Damage Response, Fibrosis and Type I Interferon Signature in Systemic Sclerosis

Increased endogenous DNA damage and type I interferon pathway activation have been implicated in systemic sclerosis (SSc) pathogenesis. Because experimental evidence suggests an interplay between DNA damage response/repair (DDR/R) and immune response, we hypothesized that deregulated DDR/R is associ...

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Detalles Bibliográficos
Autores principales: Vlachogiannis, Nikolaos I., Pappa, Maria, Ntouros, Panagiotis A., Nezos, Adrianos, Mavragani, Clio P., Souliotis, Vassilis L., Sfikakis, Petros P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566292/
https://www.ncbi.nlm.nih.gov/pubmed/33123169
http://dx.doi.org/10.3389/fimmu.2020.582401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566292/
https://www.ncbi.nlm.nih.gov/pubmed/33123169
http://dx.doi.org/10.3389/fimmu.2020.582401

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