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Thermoneutral Housing Temperature Improves Survival in a Murine Model of Polymicrobial Peritonitis

Regulatory guidelines mandate housing for laboratory mice at temperatures below their thermoneutral zone, creating chronic cold stress. However, increases in housing temperature could alter immune responses. We hypothesized housing mice at temperatures within their thermoneutral zone would improve s...

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Detalles Bibliográficos
Autores principales: Carpenter, Kelsey C., Zhou, Yesen, Hakenjos, John M., Fry, Christopher D., Nemzek, Jean A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566308/
https://www.ncbi.nlm.nih.gov/pubmed/32433210
http://dx.doi.org/10.1097/SHK.0000000000001551