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Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer’s disease

Alzheimer’s disease (AD) is a devastating neurological disorder characterized by changes in cell-type proportions and consequently marked alterations of the transcriptome. Here we use a data-driven systems biology meta-analytical approach across three human AD cohorts, encompassing six cortical brai...

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Detalles Bibliográficos
Autores principales: Morabito, Samuel, Miyoshi, Emily, Michael, Neethu, Swarup, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566321/
https://www.ncbi.nlm.nih.gov/pubmed/32803238
http://dx.doi.org/10.1093/hmg/ddaa182