Clofazimine pharmacokinetics in patients with TB: dosing implications

BACKGROUND: Clofazimine is in widespread use as a key component of drug-resistant TB regimens, but the recommended dose is not evidence based. Pharmacokinetic data from relevant patient populations are needed to inform dose optimization. OBJECTIVES: To determine clofazimine exposure, evaluate covari...

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Detalles Bibliográficos
Autores principales: Abdelwahab, Mahmoud Tareq, Wasserman, Sean, Brust, James C M, Gandhi, Neel R, Meintjes, Graeme, Everitt, Daniel, Diacon, Andreas, Dawson, Rodney, Wiesner, Lubbe, Svensson, Elin M, Maartens, Gary, Denti, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566350/
https://www.ncbi.nlm.nih.gov/pubmed/32747933
http://dx.doi.org/10.1093/jac/dkaa310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566350/
https://www.ncbi.nlm.nih.gov/pubmed/32747933
http://dx.doi.org/10.1093/jac/dkaa310

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