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Dose recommendations for gentamicin in the real-world obese population with varying body weight and renal (dys)function

BACKGROUND: The impact of weight on pharmacokinetics of gentamicin was recently elucidated for (morbidly) obese individuals with normal renal function. OBJECTIVES: To characterize the pharmacokinetics of gentamicin in real-world obese patients, ultimately to develop dose recommendations applicable a...

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Detalles Bibliográficos
Autores principales: Smit, Cornelis, van Schip, Anne M, van Dongen, Eric P A, Brüggemann, Roger J M, Becker, Matthijs L, Knibbe, Catherijne A J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566361/
https://www.ncbi.nlm.nih.gov/pubmed/32785707
http://dx.doi.org/10.1093/jac/dkaa312