CXCR1 and CXCR2 Inhibition by Ladarixin Improves Neutrophil-Dependent Airway Inflammation in Mice

RATIONALE: Increased IL-8 levels and neutrophil accumulation in the airways are common features found in patients affected by pulmonary diseases such as Asthma, Idiopathic Pulmonary Fibrosis, Influenza-A infection and COPD. Chronic neutrophilic inflammation is usually corticosteroid insensitive and...

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Detalles Bibliográficos
Autores principales: Mattos, Matheus Silverio, Ferrero, Maximiliano Ruben, Kraemer, Lucas, Lopes, Gabriel Augusto Oliveira, Reis, Diego Carlos, Cassali, Geovanni Dantas, Oliveira, Fabricio Marcus Silva, Brandolini, Laura, Allegretti, Marcello, Garcia, Cristiana Couto, Martins, Marco Aurélio, Teixeira, Mauro Martins, Russo, Remo Castro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566412/
https://www.ncbi.nlm.nih.gov/pubmed/33123138
http://dx.doi.org/10.3389/fimmu.2020.566953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566412/
https://www.ncbi.nlm.nih.gov/pubmed/33123138
http://dx.doi.org/10.3389/fimmu.2020.566953

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