TDP-43 real-time quaking induced conversion reaction optimization and detection of seeding activity in CSF of amyotrophic lateral sclerosis and frontotemporal dementia patients

The pathological deposition of the transactive response DNA-binding protein of 43 kDa occurs in the majority (∼97%) of amyotrophic lateral sclerosis and in around 45% of frontotemporal lobar degeneration cases. Amyotrophic lateral sclerosis and frontotemporal lobar degeneration clinically overlap, p...

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Detalles Bibliográficos
Autores principales: Scialò, Carlo, Tran, Thanh Hoa, Salzano, Giulia, Novi, Giovanni, Caponnetto, Claudia, Chiò, Adriano, Calvo, Andrea, Canosa, Antonio, Moda, Fabio, Caroppo, Paola, Silani, Vincenzo, Ticozzi, Nicola, Ratti, Antonia, Borroni, Barbara, Benussi, Luisa, Ghidoni, Roberta, Furlanis, Giovanni, Manganotti, Paolo, Senigagliesi, Beatrice, Parisse, Pietro, Brasselet, Romain, Buratti, Emanuele, Legname, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566418/
https://www.ncbi.nlm.nih.gov/pubmed/33094285
http://dx.doi.org/10.1093/braincomms/fcaa142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566418/
https://www.ncbi.nlm.nih.gov/pubmed/33094285
http://dx.doi.org/10.1093/braincomms/fcaa142

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