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Antioxidant Apigenin Relieves Age-Related Muscle Atrophy by Inhibiting Oxidative Stress and Hyperactive Mitophagy and Apoptosis in Skeletal Muscle of Mice

Skeletal muscle atrophy in the aged causes loss in muscle mass and functions. Naturally occurring antioxidant flavonoid apigenin is able to ameliorate obesity- and denervation-induced muscle atrophies, but its effects on age-related muscle atrophy remain unknown. We hypothesized that apigenin can re...

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Detalles Bibliográficos
Autores principales: Wang, Dongtao, Yang, Yajun, Zou, Xiaohu, Zhang, Jing, Zheng, Zena, Wang, Ziwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566467/
https://www.ncbi.nlm.nih.gov/pubmed/32857105
http://dx.doi.org/10.1093/gerona/glaa214