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Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates

Cyclodipeptide synthases (CDPSs) catalyze the synthesis of various cyclodipeptides by using two aminoacyl-tRNA (aa-tRNA) substrates in a sequential mechanism. Here, we studied binding of phenylalanyl-tRNA(Phe) to the CDPS from Candidatus Glomeribacter gigasporarum (Cglo-CDPS) by gel filtration and e...

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Detalles Bibliográficos
Autores principales: Bourgeois, Gabrielle, Seguin, Jérôme, Babin, Morgan, Gondry, Muriel, Mechulam, Yves, Schmitt, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566563/
https://www.ncbi.nlm.nih.gov/pubmed/32680846
http://dx.doi.org/10.1261/rna.075184.120