PDCD4 regulates axonal growth by translational repression of neurite growth-related genes and is modulated during nerve injury responses

Programmed cell death 4 (PDCD4) protein is a tumor suppressor that inhibits translation through the mTOR-dependent initiation factor EIF4A, but its functional role and mRNA targets in neurons remain largely unknown. Our work identified that PDCD4 is highly expressed in axons and dendrites of CNS and...

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Detalles Bibliográficos
Autores principales: Di Paolo, Andrés, Eastman, Guillermo, Mesquita-Ribeiro, Raquel, Farias, Joaquina, Macklin, Andrew, Kislinger, Thomas, Colburn, Nancy, Munroe, David, Sotelo Sosa, José R., Dajas-Bailador, Federico, Sotelo-Silveira, José R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566564/
https://www.ncbi.nlm.nih.gov/pubmed/32747606
http://dx.doi.org/10.1261/rna.075424.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566564/
https://www.ncbi.nlm.nih.gov/pubmed/32747606
http://dx.doi.org/10.1261/rna.075424.120

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