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The RNA transport factor PHAX is required for proper histone H2AX expression and DNA damage response

PHAX (phosphorylated adaptor for RNA export) promotes nuclear export of short transcripts of RNA polymerase II such as spliceosomal U snRNA precursors, as well as intranuclear transport of small nucleolar RNAs (snoRNAs). However, it remains unknown whether PHAX has other critical functions. Here we...

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Detalles Bibliográficos
Autores principales: Machitani, Mitsuhiro, Taniguchi, Ichiro, McCloskey, Asako, Suzuki, Tatsuya, Ohno, Mutsuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566570/
https://www.ncbi.nlm.nih.gov/pubmed/32759388
http://dx.doi.org/10.1261/rna.074625.120