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The RNA transport factor PHAX is required for proper histone H2AX expression and DNA damage response
PHAX (phosphorylated adaptor for RNA export) promotes nuclear export of short transcripts of RNA polymerase II such as spliceosomal U snRNA precursors, as well as intranuclear transport of small nucleolar RNAs (snoRNAs). However, it remains unknown whether PHAX has other critical functions. Here we...
Autores principales: | Machitani, Mitsuhiro, Taniguchi, Ichiro, McCloskey, Asako, Suzuki, Tatsuya, Ohno, Mutsuhito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566570/ https://www.ncbi.nlm.nih.gov/pubmed/32759388 http://dx.doi.org/10.1261/rna.074625.120 |
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