microRNA-seq of cartilage reveals an overabundance of miR-140-3p which contains functional isomiRs

miR-140 is selectively expressed in cartilage. Deletion of the entire Mir140 locus in mice results in growth retardation and early-onset osteoarthritis-like pathology; however, the relative contribution of miR-140-5p or miR-140-3p to the phenotype remains to be determined. An unbiased small RNA sequ...

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Detalles Bibliográficos
Autores principales: Woods, Steven, Charlton, Sarah, Cheung, Kat, Hao, Yao, Soul, Jamie, Reynard, Louise N., Crowe, Natalie, Swingler, Tracey E., Skelton, Andrew J., Piróg, Katarzyna A., Miles, Colin G., Tsompani, Dimitra, Jackson, Robert M., Dalmay, Tamas, Clark, Ian M., Barter, Matt J., Young, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566571/
https://www.ncbi.nlm.nih.gov/pubmed/32660984
http://dx.doi.org/10.1261/rna.075176.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566571/
https://www.ncbi.nlm.nih.gov/pubmed/32660984
http://dx.doi.org/10.1261/rna.075176.120

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