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Determination of primary microRNA processing in clinical samples by targeted pri-miR-sequencing

MicroRNA expression is important for gene regulation and deregulated microRNA expression is often observed in diseases such as cancer. The processing of primary microRNA transcripts is an important regulatory step in microRNA biogenesis. Due to low expression level and association with chromatin, pr...

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Detalles Bibliográficos
Autores principales: Conrad, Thomas, Ntini, Evgenia, Lang, Benjamin, Cozzuto, Luca, Andersen, Jesper B., Marquardt, Jens U., Ponomarenko, Julia, Tartaglia, Gian Gaetano, Vang Ørom, Ulf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566579/
https://www.ncbi.nlm.nih.gov/pubmed/32669295
http://dx.doi.org/10.1261/rna.076240.120