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CXCR4 Inhibition Counteracts Immunosuppressive Properties of Metastatic NSCLC Stem Cells

Cancer stem cells (CSCs) are functionally defined as the cell subset with greater potential to initiate and propagate tumors. Within the heterogeneous population of lung CSCs, we previously identified highly disseminating CD133+CXCR4+ cells able to initiate distant metastasis (metastasis initiating...

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Detalles Bibliográficos
Autores principales: Fortunato, Orazio, Belisario, Dimas Carolina, Compagno, Mara, Giovinazzo, Francesca, Bracci, Cristiano, Pastorino, Ugo, Horenstein, Alberto, Malavasi, Fabio, Ferracini, Riccardo, Scala, Stefania, Sozzi, Gabriella, Roz, Luca, Roato, Ilaria, Bertolini, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566588/
https://www.ncbi.nlm.nih.gov/pubmed/33123122
http://dx.doi.org/10.3389/fimmu.2020.02168