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CXCR4 Inhibition Counteracts Immunosuppressive Properties of Metastatic NSCLC Stem Cells
Cancer stem cells (CSCs) are functionally defined as the cell subset with greater potential to initiate and propagate tumors. Within the heterogeneous population of lung CSCs, we previously identified highly disseminating CD133+CXCR4+ cells able to initiate distant metastasis (metastasis initiating...
Autores principales: | Fortunato, Orazio, Belisario, Dimas Carolina, Compagno, Mara, Giovinazzo, Francesca, Bracci, Cristiano, Pastorino, Ugo, Horenstein, Alberto, Malavasi, Fabio, Ferracini, Riccardo, Scala, Stefania, Sozzi, Gabriella, Roz, Luca, Roato, Ilaria, Bertolini, Giulia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566588/ https://www.ncbi.nlm.nih.gov/pubmed/33123122 http://dx.doi.org/10.3389/fimmu.2020.02168 |
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