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PRMT5/Wnt4 axis promotes lymph-node metastasis and proliferation of laryngeal carcinoma

Metastasis is the main cause of laryngeal cancer-related death; its molecular mechanism remains unknown. Here we identify protein arginine methyltransferase 5 (PRMT5) as a new metastasis-promoting factor in laryngeal carcinoma, and explore its underlying mechanism of action in regulating laryngeal c...

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Detalles Bibliográficos
Autores principales: Wang, Nan, Yan, Honghong, Wu, Di, Zhao, Zheng, Chen, Xiaoqi, Long, Qian, Zhang, Changlin, Wang, Xiaohao, Deng, Wuguo, Liu, Xuekui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566595/
https://www.ncbi.nlm.nih.gov/pubmed/33060569
http://dx.doi.org/10.1038/s41419-020-03064-x