Cargando…

PRMT5/Wnt4 axis promotes lymph-node metastasis and proliferation of laryngeal carcinoma

Metastasis is the main cause of laryngeal cancer-related death; its molecular mechanism remains unknown. Here we identify protein arginine methyltransferase 5 (PRMT5) as a new metastasis-promoting factor in laryngeal carcinoma, and explore its underlying mechanism of action in regulating laryngeal c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Nan, Yan, Honghong, Wu, Di, Zhao, Zheng, Chen, Xiaoqi, Long, Qian, Zhang, Changlin, Wang, Xiaohao, Deng, Wuguo, Liu, Xuekui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566595/ https://www.ncbi.nlm.nih.gov/pubmed/33060569 http://dx.doi.org/10.1038/s41419-020-03064-x

Ejemplares similares

Dysregulated YY1/PRMT5 axis promotes the progression and metastasis of laryngeal cancer by targeting Hippo pathway
por: Wang, Nan, et al.
Publicado: (2020)

Lymph Node Ratio for Postoperative Staging of Laryngeal Squamous Cell Carcinoma with Lymph Node Metastasis
por: Wang, Yu-Long, et al.
Publicado: (2014)

The Prognostic Significance of Lymph Node Ratio and Log Odds Ratio in Laryngeal Squamous Cell Carcinoma
por: Zhang, Xinrui, et al.
Publicado: (2018)

Vasculogenic mimicry contributes to lymph node metastasis of laryngeal squamous cell carcinoma
por: Wang, Wei, et al.
Publicado: (2010)

A rare case of a laryngeal leiomyosarcoma with a lymph node metastasis
por: Salama, Khadija, et al.
Publicado: (2021)

A Rare Case of Inguinal Lymph Node Metastasis from Supraglottic Laryngeal Carcinoma
por: Das, Soumen, et al.
Publicado: (2011)

A Predictive Nomogram for Lymph Node Metastasis in Supraglottic Laryngeal Squamous Cell Carcinoma
por: Song, Lulu, et al.
Publicado: (2022)

Microarray Gene Expression Analysis of Tumorigenesis and Regional Lymph Node Metastasis in Laryngeal Squamous Cell Carcinoma
por: Lian, Meng, et al.
Publicado: (2013)

Topographic distribution of lymph node metastasis in patients with stage IB1 cervical cancer: an analysis of 8314 lymph nodes
por: Cai, Jing, et al.
Publicado: (2021)

Model of lymph node metastasis posterior to the right recurrent laryngeal nerve in papillary thyroid carcinoma
por: Luo, Yi, et al.
Publicado: (2018)

Lymph node metastasis around the entrance point to recurrent laryngeal nerve in papillary thyroid carcinoma
por: Lv, Tian, et al.
Publicado: (2020)

Differentially expressed genes related to lymph node metastasis in advanced laryngeal squamous cell cancers
por: Bayır, Ömer, et al.
Publicado: (2022)

Application of an Interpretable Machine Learning Model to Predict Lymph Node Metastasis in Patients with Laryngeal Carcinoma
por: Feng, Menglong, et al.
Publicado: (2022)

Pattern and Predictive Factors of Metastasis in Lymph Nodes Posterior to the Right Recurrent Laryngeal Nerve in Papillary Thyroid Carcinoma
por: Zhou, Mengqian, et al.
Publicado: (2022)

Application of Endobronchial Ultrasonography for the Preoperative Detecting Recurrent Laryngeal Nerve Lymph Node Metastasis of Esophageal Cancer
por: Shan, Hong-Bo, et al.
Publicado: (2015)

Patterns of cervical lymph node metastasis in supraglottic laryngeal cancer and therapeutic implications of surgical staging of the neck
por: Kürten, Cornelius H. L., et al.
Publicado: (2021)

MMP-9 and CCR7 as Possible Predictors of Lymph Node Metastasis in Laryngeal Squamous Cell Carcinoma
por: Rachmadi, Lisnawati, et al.
Publicado: (2023)

PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression
por: Li, Zhongwei, et al.
Publicado: (2023)

Development of a prediction model for the risk of recurrent laryngeal nerve lymph node metastasis in thoracolaparoscopic esophagectomy with cervical anastomosis
por: Zhang, Guoqing, et al.
Publicado: (2021)

Prognostic importance of harvested lymph node number, metastatic lymph node number, and lymph node ratio in surgically managed laryngeal squamous cell carcinoma
por: Abakay, Mehmet Akif, et al.
Publicado: (2020)

Risk factors for lymph node metastasis of the left recurrent laryngeal nerve in patients with esophageal squamous cell carcinoma
por: Chen, Chuangui, et al.
Publicado: (2021)

Clinical Relevance and Management of Recurrent Laryngeal Nerve Inlet Zone Lymph Nodes Metastasis in Papillary Thyroid Cancer
por: Zheng, Guibin, et al.
Publicado: (2021)

Multimodal predictive factors of metastasis in lymph nodes posterior to the right recurrent laryngeal nerve in papillary thyroid carcinoma
por: Gong, Yi, et al.
Publicado: (2023)

ADAM17 promotes lymph node metastasis in gastric cancer via activation of the Notch and Wnt signaling pathways
por: Li, Wei, et al.
Publicado: (2019)

Targeting Lymph Node Sinus Macrophages to Inhibit Lymph Node Metastasis
por: Hu, Junqing, et al.
Publicado: (2019)

Lymph node metastasis pattern and significance of left gastric artery lymph node dissection in esophagectomy for esophageal cancers
por: Deng, Xiu-Mei, et al.
Publicado: (2021)

A Dual-Energy CT Radiomics of the Regional Largest Short-Axis Lymph Node Can Improve the Prediction of Lymph Node Metastasis in Patients With Rectal Cancer
por: Wang, Dongqing, et al.
Publicado: (2022)

PRMT5/FGFR3/AKT Signaling Axis Facilitates Lung Cancer Cell Metastasis
por: Zheng, Yonghua, et al.
Publicado: (2023)

Lymph Nodes Dissection in Elderly Patients with T3-T4 Laryngeal Cancer
por: Pan, Yafeng, et al.
Publicado: (2020)

Metastasis of cN0 Papillary Thyroid Carcinoma of the Isthmus to the Lymph Node Posterior to the Right Recurrent Laryngeal Nerve
por: Du, Wei, et al.
Publicado: (2021)

Expression of prostate-specific membrane antigen in the neovasculature of primary tumors and lymph node metastasis of laryngeal squamous cell carcinomas
por: Erkılınç, Gamze, et al.
Publicado: (2022)

Process of distant lymph node metastasis in colorectal carcinoma: Implication of extracapsular invasion of lymph node metastasis
por: Fujii, Takaaki, et al.
Publicado: (2011)

The Role of the PRMT5–SND1 Axis in Hepatocellular Carcinoma
por: Wright, Tanner, et al.
Publicado: (2021)

Metadherin–PRMT5 complex enhances the metastasis of hepatocellular carcinoma through the WNT–β-catenin signaling pathway
por: Zhu, Kai, et al.
Publicado: (2020)

Does recurrent laryngeal nerve lymph node metastasis really affect the prognosis in node-positive patients with squamous cell carcinoma of the middle thoracic esophagus?
por: Wu, Jie, et al.
Publicado: (2014)

Regulation of a PRMT5/NF-κB Axis by Phosphorylation of PRMT5 at Serine 15 in Colorectal Cancer
por: Hartley, Antja-Voy, et al.
Publicado: (2020)

Breast Axillary Lymph Node Metastasis
por: Cavalli, Luciane R., et al.
Publicado: (2011)

Lymph Node Metastasis of Gastric Cancer
por: Akagi, Tomonori, et al.
Publicado: (2011)

The role of the endothelin axis in promoting epithelial to mesenchymal transition and lymph node metastasis in prostate adenocarcinoma
por: Papanikolaou, Sophia, et al.
Publicado: (2017)

CXCR7/CXCL12 axis is involved in lymph node and liver metastasis of gastric carcinoma
por: Xin, Qi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_gh8g5h29jshicmvglhq0h9qr9l