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A C-peptide complex with albumin and Zn(2+) increases measurable GLUT1 levels in membranes of human red blood cells

People with type 1 diabetes (T1D) require exogenous administration of insulin, which stimulates the translocation of the GLUT4 glucose transporter to cell membranes. However, most bloodstream cells contain GLUT1 and are not directly affected by insulin. Here, we report that C-peptide, the 31-amino a...

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Detalles Bibliográficos
Autores principales: Geiger, M., Janes, T., Keshavarz, H., Summers, S., Pinger, C., Fletcher, D., Zinn, K., Tennakoon, M., Karunarathne, A., Spence, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566639/
https://www.ncbi.nlm.nih.gov/pubmed/33060722
http://dx.doi.org/10.1038/s41598-020-74527-6