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PPP2R2D suppresses IL-2 production and Treg function

Protein phosphatase 2A is a ubiquitously expressed serine/threonine phosphatase that comprises a scaffold, a catalytic, and multiple regulatory subunits and has been shown to be important in the expression of autoimmunity. We considered that a distinct subunit may account for the decreased productio...

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Detalles Bibliográficos
Autores principales: Pan, Wenliang, Sharabi, Amir, Ferretti, Andrew, Zhang, Yinfeng, Burbano, Catalina, Yoshida, Nobuya, Tsokos, Maria G., Tsokos, George C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566706/
https://www.ncbi.nlm.nih.gov/pubmed/32897879
http://dx.doi.org/10.1172/jci.insight.138215